Rutin and Hesperidin Alleviate Paclitaxel-Induced Nephrocardiotoxicity in Wistar Rats via Suppressing the Oxidative Stress and Enhancing the Antioxidant Defense Mechanisms

Paclitaxel is a primary chemotherapy agent that displays antitumor activity against a variety of solid tumors. However, the clinical effectiveness of the drug is hampered by its nephrotoxic and cardiotoxic side effects. Thus, this investigation aimed at assessing the protective effects of rutin, hes...

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Detalles Bibliográficos
Autores principales: Ali, Yasmine A., Ahmed, Osama M., Soliman, Hanan A., Abdel-Gabbar, Mohamed, Al-Dossari, M., El-Gawaad, N. S. Abd, El-Nahass, El-Shaymaa, Ahmed, Noha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977529/
https://www.ncbi.nlm.nih.gov/pubmed/36874615
http://dx.doi.org/10.1155/2023/5068304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977529/
https://www.ncbi.nlm.nih.gov/pubmed/36874615
http://dx.doi.org/10.1155/2023/5068304

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