Design, synthesis, and biological evaluation of new 2-(4-(methylsulfonyl)phenyl)-N-phenylimidazo[1,2-a]pyridin-3-amine as selective COX-2 inhibitors

Cyclooxygenase (COX), which plays a role in converting arachidonic acid to inflammatory mediators, could be inhibited by non-steroidal anti-inflammatory drugs (NSAIDs). Although potent NSAIDs are available for the treatment of pain, fever, and inflammation, some side effects, such as gastrointestina...

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Detalles Bibliográficos
Autores principales: Movahed, Mahsa Azami, Abbasi, Fatemeh Khadem, Rajabi, Mahsa, Abedi, Niusha, Naderi, Nima, Daraei, Bahram, Zarghi, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977638/
https://www.ncbi.nlm.nih.gov/pubmed/37056461
http://dx.doi.org/10.1007/s00044-023-03041-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977638/
https://www.ncbi.nlm.nih.gov/pubmed/37056461
http://dx.doi.org/10.1007/s00044-023-03041-x

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