ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2‐stabilized PINK1/Parkin‐mediated mitophagy

We investigated the role of zinc‐finger protein 281 (ZNF281), a novel molecule, in ethanol‐induced hepatocyte senescence and uncovered the potential mechanism. Real‐time PCR, Western blot, immunofluorescence staining, and enzyme‐linked immunosorbent assay were performed to explore the role of ZNF281...

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Detalles Bibliográficos
Autores principales: Lu, Chunfeng, Ge, Ting, Shao, Yunyun, Cui, Wenqian, Li, Zhe, Xu, Wenxuan, Bao, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977663/
https://www.ncbi.nlm.nih.gov/pubmed/36514923
http://dx.doi.org/10.1111/cpr.13378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977663/
https://www.ncbi.nlm.nih.gov/pubmed/36514923
http://dx.doi.org/10.1111/cpr.13378

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