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ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2‐stabilized PINK1/Parkin‐mediated mitophagy
We investigated the role of zinc‐finger protein 281 (ZNF281), a novel molecule, in ethanol‐induced hepatocyte senescence and uncovered the potential mechanism. Real‐time PCR, Western blot, immunofluorescence staining, and enzyme‐linked immunosorbent assay were performed to explore the role of ZNF281...
Autores principales: | Lu, Chunfeng, Ge, Ting, Shao, Yunyun, Cui, Wenqian, Li, Zhe, Xu, Wenxuan, Bao, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977663/ https://www.ncbi.nlm.nih.gov/pubmed/36514923 http://dx.doi.org/10.1111/cpr.13378 |
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