CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions

Exposure of lipopolysaccharide triggers macrophage pro-inflammatory polarization accompanied by metabolic reprogramming, characterized by elevated aerobic glycolysis and a broken tricarboxylic acid cycle. However, in contrast to lipopolysaccharide, CD40 signal is able to drive pro-inflammatory and a...

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Detalles Bibliográficos
Autores principales: Liu, Pu-Ste, Chen, Yi-Ting, Li, Xiaoyun, Hsueh, Pei-Chun, Tzeng, Sheue-Fen, Chen, Hsi, Shi, Pei-Zhu, Xie, Xin, Parik, Sweta, Planque, Mélanie, Fendt, Sarah-Maria, Ho, Ping-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977680/
https://www.ncbi.nlm.nih.gov/pubmed/36823405
http://dx.doi.org/10.1038/s41590-023-01430-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977680/
https://www.ncbi.nlm.nih.gov/pubmed/36823405
http://dx.doi.org/10.1038/s41590-023-01430-3

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