Maximum dose, safety, tolerability and ketonemia after triheptanoin in glucose transporter type 1 deficiency (G1D)

Augmentation of anaplerosis, or replenishment of carbon lost during intermediary metabolic transitions, is desirable in energy metabolism defects. Triheptanoin, the triglyceride of 7-carbon heptanoic acid, is anaplerotic via direct oxidation or 5-carbon ketone body generation. In this context, trihe...

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Detalles Bibliográficos
Autores principales: Málaga, Ignacio, Avila, Adrian, Primeaux, Sharon, Kallem, Raja Reddy, Roe, Charles R., Putnam, William C., Park, Jason Y., Shinnar, Shlomo, Ahn, Chul, Pascual, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977760/
https://www.ncbi.nlm.nih.gov/pubmed/36859467
http://dx.doi.org/10.1038/s41598-023-30578-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977760/
https://www.ncbi.nlm.nih.gov/pubmed/36859467
http://dx.doi.org/10.1038/s41598-023-30578-z

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