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The Neuropilin-1/PKC axis promotes neuroendocrine differentiation and drug resistance of prostate cancer

BACKGROUND: Neuroendocrine prostate cancer (NEPC) is a multi-resistant variant of prostate cancer (PCa) that has become a major challenge in clinics. Understanding the neuroendocrine differentiation (NED) process at the molecular level is therefore critical to define therapeutic strategies that can...

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Detalles Bibliográficos
Autores principales: Blanc, Charly, Moktefi, Anissa, Jolly, Ariane, de la Grange, Pierre, Gay, Denise, Nicolaiew, Nathalie, Semprez, Fannie, Maillé, Pascale, Soyeux, Pascale, Firlej, Virginie, Vacherot, Francis, Destouches, Damien, Amiche, Mohamed, Terry, Stéphane, de la Taille, Alexandre, Londoño-Vallejo, Arturo, Allory, Yves, Delbé, Jean, Hamma-Kourbali, Yamina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977768/
https://www.ncbi.nlm.nih.gov/pubmed/36550208
http://dx.doi.org/10.1038/s41416-022-02114-9