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Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function

Autotransporters (ATs) are a large family of bacterial secreted and outer membrane proteins that encompass a wide range of enzymatic activities frequently associated with pathogenic phenotypes. We present the structural and functional characterisation of a subtilase autotransporter, Ssp, from the op...

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Detalles Bibliográficos
Autores principales: Hor, Lilian, Pilapitiya, Akila, McKenna, James A., Panjikar, Santosh, Anderson, Marilyn A., Desvaux, Mickaël, Paxman, Jason J., Heras, Begoña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977779/
https://www.ncbi.nlm.nih.gov/pubmed/36859523
http://dx.doi.org/10.1038/s41467-023-36719-2