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Resveratrol suppresses neuroinflammation to alleviate mechanical allodynia by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in a rat model of spinal cord injury

BACKGROUND: Neuropathic pain (NP) is one of intractable complications of spinal cord injury (SCI) and lacks effective treatment. Resveratrol (Res) has been shown to possess potent anti-inflammatory and anti-nociceptive effects. In this study, we investigated the analgesic effect of Res and its under...

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Detalles Bibliográficos
Autores principales: Han, Jie, Hua, Zhen, Yang, Wen-jie, Wang, Shu, Yan, Fang, Wang, Jun-nan, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977815/
https://www.ncbi.nlm.nih.gov/pubmed/36873101
http://dx.doi.org/10.3389/fnmol.2023.1116679