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Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis

Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC proliferation and fates. Their developmental origins are largely unknown. In zebrafish, we previously found that the stromal cells of the caudal hematopoietic tissue (CHT), a n...

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Detalles Bibliográficos
Autores principales: Murayama, Emi, Vivier, Catherine, Schmidt, Anne, Herbomel, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977867/
https://www.ncbi.nlm.nih.gov/pubmed/36859431
http://dx.doi.org/10.1038/s41467-023-36612-y