Claudin-10b cation channels in tight junction strands: Octameric-interlocked pore barrels constitute paracellular channels with low water permeability

Claudin proteins constitute the backbone of tight junctions (TJs) regulating paracellular permeability for solutes and water. The molecular mechanism of claudin polymerization and paracellular channel formation is unclear. However, a joined double-rows architecture of claudin strands has been suppor...

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Detalles Bibliográficos
Autores principales: Nagarajan, Santhosh Kumar, Klein, Stanislav, Fadakar, Bita Sokhandan, Piontek, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977872/
https://www.ncbi.nlm.nih.gov/pubmed/36874155
http://dx.doi.org/10.1016/j.csbj.2023.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977872/
https://www.ncbi.nlm.nih.gov/pubmed/36874155
http://dx.doi.org/10.1016/j.csbj.2023.02.009

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