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Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption

Crocodilians are an order of ancient reptiles that thrive in pathogen-rich environments. The ability to inhabit these harsh environments is indicative of a resilient innate immune system. Defensins, a family of cysteine-rich cationic host defence peptides, are a major component of the innate immune...

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Detalles Bibliográficos
Autores principales: Williams, Scott A., Lay, Fung T., Bindra, Guneet K., Banjara, Suresh, Poon, Ivan K. H., Phan, Thanh Kha, Kvansakul, Marc, Hulett, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977887/
https://www.ncbi.nlm.nih.gov/pubmed/36859344
http://dx.doi.org/10.1038/s41467-023-36280-y