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Sequence terminus dependent PCR for site-specific mutation and modification detection

The detection of changes in nucleic acid sequences at specific sites remains a critical challenge in epigenetics, diagnostics and therapeutics. To date, such assays often require extensive time, expertise and infrastructure for their implementation, limiting their application in clinical settings. H...

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Detalles Bibliográficos
Autores principales: Xu, Gaolian, Yang, Hao, Qiu, Jiani, Reboud, Julien, Zhen, Linqing, Ren, Wei, Xu, Hong, Cooper, Jonathan M., Gu, Hongchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978023/
https://www.ncbi.nlm.nih.gov/pubmed/36859350
http://dx.doi.org/10.1038/s41467-023-36884-4