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Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease

Placental abnormalities have been sporadically implicated as a source of developmental heart defects. Yet it remains unknown how often the placenta is at the root of congenital heart defects (CHDs), and what the cellular mechanisms are that underpin this connection. Here, we selected three mouse mut...

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Detalles Bibliográficos
Autores principales: Radford, Bethany N., Zhao, Xiang, Glazer, Tali, Eaton, Malcolm, Blackwell, Danielle, Mohammad, Shuhiba, Lo Vercio, Lucas Daniel, Devine, Jay, Shalom-Barak, Tali, Hallgrimsson, Benedikt, Cross, James C., Sucov, Henry M., Barak, Yaacov, Dean, Wendy, Hemberger, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978031/
https://www.ncbi.nlm.nih.gov/pubmed/36859534
http://dx.doi.org/10.1038/s41467-023-36740-5