Bone tumor-homing nanotherapeutics for prolonged retention in tumor microenvironment and facilitated apoptotic process via mevalonate pathway inhibition

Bone malignancy features a mineralized extracellular matrix primarily composed of hydroxyapatite, which interferes with the distribution and activity of antineoplastic agents. Herein, we report bone tumor-homing polymeric nanotherapeutics consisting of alendronate-decorated chondroitin sulfate A-gra...

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Detalles Bibliográficos
Autores principales: Kang, Nae-Won, Visetvichaporn, Voradanu, Nguyen, Duy-Thuc, Shin, Eun Kyung, Kim, Dahan, Kim, Min-Jae, Yoo, So-Yeol, Lee, Jae-Young, Kim, Dae-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978036/
https://www.ncbi.nlm.nih.gov/pubmed/36873733
http://dx.doi.org/10.1016/j.mtbio.2023.100591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978036/
https://www.ncbi.nlm.nih.gov/pubmed/36873733
http://dx.doi.org/10.1016/j.mtbio.2023.100591

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