APOE-ε4 modulates the association between regional amyloid deposition and cognitive performance in cognitively unimpaired middle-aged individuals

PURPOSE: To determine whether the APOE-ε4 allele modulates the relationship between regional β-amyloid (Aβ) accumulation and cognitive change in middle-aged cognitively unimpaired (CU) participants. METHODS: The 352 CU participants (mean aged 61.1 [4.7] years) included completed two cognitive assess...

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Detalles Bibliográficos
Autores principales: Brugulat-Serrat, Anna, Sánchez-Benavides, Gonzalo, Cacciaglia, Raffaele, Salvadó, Gemma, Shekari, Mahnaz, Collij, Lyduine E., Buckley, Christopher, van Berckel, Bart N. M., Perissinotti, Andrés, Niñerola-Baizán, Aida, Milà-Alomà, Marta, Vilor-Tejedor, Natàlia, Operto, Grégory, Falcon, Carles, Grau-Rivera, Oriol, Arenaza-Urquijo, Eider M., Minguillón, Carolina, Fauria, Karine, Molinuevo, José Luis, Suárez-Calvet, Marc, Gispert, Juan Domingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978048/
https://www.ncbi.nlm.nih.gov/pubmed/36856866
http://dx.doi.org/10.1186/s13550-023-00967-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978048/
https://www.ncbi.nlm.nih.gov/pubmed/36856866
http://dx.doi.org/10.1186/s13550-023-00967-6

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