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Roles of conserved active site residues in the IscS cysteine desulfurase reaction
Escherichia coli cysteine desulfurase (CD), IscS, modifies basal metabolism by transferring sulphur (S) from L-cysteine to numerous cellular pathways, whereas NFS1, a human CD, is active only in the formation of the [Acp](2):[ISD11](2):[NFS1](2) complex. Despite the accumulation of red-coloured IscS...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978102/ https://www.ncbi.nlm.nih.gov/pubmed/36876095 http://dx.doi.org/10.3389/fmicb.2023.1084205 |