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Roles of conserved active site residues in the IscS cysteine desulfurase reaction

Escherichia coli cysteine desulfurase (CD), IscS, modifies basal metabolism by transferring sulphur (S) from L-cysteine to numerous cellular pathways, whereas NFS1, a human CD, is active only in the formation of the [Acp](2):[ISD11](2):[NFS1](2) complex. Despite the accumulation of red-coloured IscS...

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Detalles Bibliográficos
Autores principales: Pang, Yilin, Wang, Jing, Gao, Xueping, Jiang, Mengyao, Zhu, Lifei, Liang, Feng, Liang, Mengxiang, Wu, Xiaolin, Xu, Xianxian, Ren, Xiaojun, Xie, Ting, Wang, Wu, Sun, Qianqian, Xiong, Xiaojun, Lyu, Jianxin, Li, Jianghui, Tan, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978102/
https://www.ncbi.nlm.nih.gov/pubmed/36876095
http://dx.doi.org/10.3389/fmicb.2023.1084205