Characterization of clonal immunoglobulin heavy V-D-J gene rearrangements in Chinese patients with chronic lymphocytic leukemia: Clinical features and molecular profiles

INTRODUCTION: Several prognostic factors of chronic lymphocytic leukemia (CLL) have been identified, such as cytogenetic aberrations and recurrent gene mutations. B-cell receptor (BCR) signaling plays an important role in the tumorigenesis of CLL, and its clinical significance in predicting prognosi...

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Detalles Bibliográficos
Autores principales: Deng, Xinyue, Zhang, Meilan, Wang, Jiachen, Zhou, Xiaoxi, Xiao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978106/
https://www.ncbi.nlm.nih.gov/pubmed/36874132
http://dx.doi.org/10.3389/fonc.2023.1120867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978106/
https://www.ncbi.nlm.nih.gov/pubmed/36874132
http://dx.doi.org/10.3389/fonc.2023.1120867

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