Cargando…

Characterization of clonal immunoglobulin heavy V-D-J gene rearrangements in Chinese patients with chronic lymphocytic leukemia: Clinical features and molecular profiles

INTRODUCTION: Several prognostic factors of chronic lymphocytic leukemia (CLL) have been identified, such as cytogenetic aberrations and recurrent gene mutations. B-cell receptor (BCR) signaling plays an important role in the tumorigenesis of CLL, and its clinical significance in predicting prognosi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Xinyue, Zhang, Meilan, Wang, Jiachen, Zhou, Xiaoxi, Xiao, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978106/ https://www.ncbi.nlm.nih.gov/pubmed/36874132 http://dx.doi.org/10.3389/fonc.2023.1120867

Ejemplares similares

Immunoglobulin gene rearrangements in Chinese and Italian patients with chronic lymphocytic leukemia
por: Marinelli, Marilisa, et al.
Publicado: (2016)

Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia
por: Kolijn, P. Martijn, et al.
Publicado: (2021)

Characterization of clonal immunoglobulin heavy (IGH) V-D-J gene rearrangements and the complementarity-determining region in South Indian patients with precursor B-cell acute lymphoblastic leukemia
por: Sudhakar, Natarajan, et al.
Publicado: (2017)

Nanopore sequencing of clonal IGH rearrangements in cell-free DNA as a biomarker for acute lymphoblastic leukemia
por: Sampathi, Shilpa, et al.
Publicado: (2022)

Clonal Evolution of High-Risk Chronic Lymphocytic Leukemia: A Contemporary Perspective
por: Kwok, Marwan, et al.
Publicado: (2021)

The Importance of an In-depth Study of Immunoglobulin Gene Rearrangements When Ascertaining the Clonal Relationship between Concomitant Chronic Lymphocytic Leukemia and Multiple Myeloma
por: Trudel, Stéphanie, et al.
Publicado: (2016)

Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements
por: Bagnara, Davide, et al.
Publicado: (2022)

Distinct Age-Related Clinical Features and Risk Assessment in Chinese With Chronic Lymphocytic Leukemia
por: Tian, Zheng, et al.
Publicado: (2022)

Erratum to: Partial versus Productive Immunoglobulin Heavy Locus Rearrangements in Chronic Lymphocytic Leukemia: Implications for B-Cell Receptor Stereotypy
por: Tsakou, Eugenia, et al.
Publicado: (2013)

High frequency of clonal immunoglobulin or T cell receptor gene rearrangements in acute myelogenous leukemia expressing terminal deoxyribonucleotidyltransferase
Publicado: (1987)

Clinical implication of minimal residual disease assessment by next-generation sequencing-based immunoglobulin clonality assay in pediatric B-acute lymphoblastic leukemia
por: Lee, Jae Wook, et al.
Publicado: (2022)

IGH Translocations in Chinese Patients With Chronic Lymphocytic Leukemia: Clinicopathologic Characteristics and Genetic Profile
por: Li, Qinlu, et al.
Publicado: (2022)

Clonality assessment and detection of clonal diversity in classic Hodgkin lymphoma by next-generation sequencing of immunoglobulin gene rearrangements
por: van Bladel, Diede A. G., et al.
Publicado: (2021)

Treatment Approaches to Chronic Lymphocytic Leukemia With High-Risk Molecular Features
por: van der Straten, Lina, et al.
Publicado: (2021)

KSHV induces immunoglobulin rearrangements in mature B lymphocytes
por: Totonchy, Jennifer, et al.
Publicado: (2018)

Submicroscopic Deletions of Immunoglobulin Heavy Chain Gene (IGH) in Precursor B Lymphoblastic Leukemia with IGH Rearrangements
por: Huh, Jungwon, et al.
Publicado: (2015)

A Unique Human Immunoglobulin Heavy Chain Variable Domain-Only CD33 CAR for the Treatment of Acute Myeloid Leukemia
por: Schneider, Dina, et al.
Publicado: (2018)

Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS
por: Scheijen, Blanca, et al.
Publicado: (2019)

Correction to: Clonality assessment and detection of clonal diversity in classic Hodgkin lymphoma by next-generation sequencing of immunoglobulin gene rearrangements
por: van Bladel, Diede A. G., et al.
Publicado: (2021)

Monoclonal immunoglobulin heavy chain gene rearrangement in Fuchs’ uveitis
por: Nakahara, Hisae, et al.
Publicado: (2018)

Immunoglobulin Heavy Chain Gene Rearrangements in Patients with Gaucher Disease
por: Rodić, Predrag, et al.
Publicado: (2018)

Prognostic value of bone marrow involvement by clonal immunoglobulin gene rearrangements in follicular lymphoma
por: Berget, Ellen, et al.
Publicado: (2014)

Case Report: Chronic Lymphocytic Leukemia With a Rare Translocation t(14;19)(q32;q13) Involving IGH/BCL3 Rearrangements: Report of Three Chinese Cases and Literature Review
por: Li, Qinlu, et al.
Publicado: (2020)

Case report: Genomic analysis of a therapy-related chronic myelomonocytic leukemia with KMT2A rearrangement that progressed to acute myeloid leukemia with acute promyelocytic leukemia-like features
por: Suzuki, Tomotaka, et al.
Publicado: (2023)

Chronic lymphocytic leukemia presenting with ascites diagnosed by clonality analysis via gene rearrangement assay: A case report
por: HUANG, YEN-MIN, et al.
Publicado: (2014)

Mutation Status and Immunoglobulin Gene Rearrangements in Patients from Northwest and Central Region of Spain with Chronic Lymphocytic Leukemia
por: González-Gascón y Marín, I., et al.
Publicado: (2014)

First Case of Transformation of Immunoglobulin Heavy Chain Variable-Mutated Chronic Lymphocytic Leukemia Into Chronic Myeloid Leukemia
por: Zhang, Xueya, et al.
Publicado: (2019)

T cell receptor and immunoglobulin gene rearrangements in acute myeloblastic leukemia
Publicado: (1986)

A Case of T-Cell Large Granular Lymphocytic Leukemia and Renal Immunoglobulin Heavy Chain Amyloidosis
por: Fu, Julie, et al.
Publicado: (2019)

ImmunoGlobulin galaxy (IGGalaxy) for simple determination and quantitation of immunoglobulin heavy chain rearrangements from NGS
por: Moorhouse, Michael J, et al.
Publicado: (2014)

Comprehensive characterization of immunoglobulin gene rearrangements in patients with chronic lymphocytic leukaemia
por: René, Céline, et al.
Publicado: (2014)

Atypical Rearrangements in APL-Like Acute Myeloid Leukemias: Molecular Characterization and Prognosis
por: Guarnera, Luca, et al.
Publicado: (2022)

Detection of Immunoglobulin Heavy Chain Gene Clonality by Next-Generation Sequencing for Minimal Residual Disease Monitoring in B-Lymphoblastic Leukemia
por: Shin, Saeam, et al.
Publicado: (2017)

Dogs with Acute Myeloid Leukemia Have Clonal Rearrangements in T and B Cell Receptors
por: Stokol, Tracy, et al.
Publicado: (2017)

Read the clonotype: Next-generation sequencing-based lymphocyte clonality analysis and perspectives for application in pathology
por: Groenen, Patricia J. T. A., et al.
Publicado: (2023)

Telomere Dysfunction in Chronic Lymphocytic Leukemia
por: Jebaraj, Billy Michael Chelliah, et al.
Publicado: (2021)

An updated perspective on immunoglobulin replacement in chronic lymphocytic leukaemia in the era of targeted therapies
por: Khan, Sujoy, et al.
Publicado: (2023)

Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia
por: Cheung, Laurence C., et al.
Publicado: (2021)

De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia
por: Hyrenius-Wittsten, Axel, et al.
Publicado: (2018)

Preferential use of unmutated immunoglobulin heavy variable region genes in Boxer dogs with chronic lymphocytic leukemia
por: Rout, Emily D., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pv9k85gakm9v8oiftm3f2l5k1t