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Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks

Neurons in vitro connect to each other and form neural networks that display emergent electrophysiological activity. This activity begins as spontaneous uncorrelated firing in the early phase of development, and as functional excitatory and inhibitory synapses mature, the activity typically emerges...

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Detalles Bibliográficos
Autores principales: Weir, Janelle Shari, Christiansen, Nicholas, Sandvig, Axel, Sandvig, Ioanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978115/
https://www.ncbi.nlm.nih.gov/pubmed/36874945
http://dx.doi.org/10.3389/fncir.2023.1020487