Crebanine induces ROS-dependent apoptosis in human hepatocellular carcinoma cells via the AKT/FoxO3a signaling pathway

Background: Hepatocellular carcinoma (HCC), as an aggressive cancer with a high mortality rate, needs high-efficiency and low-toxicity drug therapy. Natural products have great potential as candidate lead compounds for the development of new HCC drugs. Crebanine is an isoquinoline alkaloid derived f...

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Detalles Bibliográficos
Autores principales: Tan, Jiajie, Xiang, Yuling, Xiong, Yuanguo, Zhang, Yaoyuan, Qiao, Boyang, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978116/
https://www.ncbi.nlm.nih.gov/pubmed/36874025
http://dx.doi.org/10.3389/fphar.2023.1069093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978116/
https://www.ncbi.nlm.nih.gov/pubmed/36874025
http://dx.doi.org/10.3389/fphar.2023.1069093

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