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RNA-Seq analysis of obese Pdha1(fl/fl)Lyz2-Cre mice induced by a high-fat diet

Pyruvate dehydrogenase complex (PDH) is an important complex of three enzymes that transforms pyruvate into acetyl-CoA, subsequently entering the tricarboxylic acid (TCA) cycle to produce ATP and electron donors. As a key regulator of energy and metabolic homeostasis, PDH is considered a potential t...

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Detalles Bibliográficos
Autores principales: Geng, Zhaohong, Yuan, Yuchan, He, Dan, Lee, Hewang, Wang, Hongyan, Niu, Nan, Ni, Zhigang, Abdullah, Shopit, Tang, Zeyao, Qu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978130/
https://www.ncbi.nlm.nih.gov/pubmed/36288929
http://dx.doi.org/10.1538/expanim.22-0054