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Deficiency in the cell-adhesion molecule dscaml1 impairs hypothalamic CRH neuron development and perturbs normal neuroendocrine stress axis function

The corticotropin-releasing hormone (CRH)-expressing neurons in the hypothalamus are critical regulators of the neuroendocrine stress response pathway, known as the hypothalamic-pituitary-adrenal (HPA) axis. As developmental vulnerabilities of CRH neurons contribute to stress-associated neurological...

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Detalles Bibliográficos
Autores principales: Ma, Manxiu, Brunal, Alyssa A., Clark, Kareem C., Studtmann, Carleigh, Stebbins, Katelyn, Higashijima, Shin-ichi, Pan, Y. Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978177/
https://www.ncbi.nlm.nih.gov/pubmed/36875755
http://dx.doi.org/10.3389/fcell.2023.1113675