Is type 2 diabetes associated dementia a microvascular early-Alzheimer’s phenotype induced by aberrations in the peripheral metabolism of lipoprotein-amyloid?

There is increasing evidence of a positive association of type 2 diabetes with Alzheimer’s disease (AD), the most prevalent form of dementia. Suggested pathways include cerebral vascular dysfunction; central insulin resistance, or exaggerated brain abundance of potentially cytotoxic amyloid-β (Aβ),...

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Detalles Bibliográficos
Autores principales: Takechi, Ryusuke, Sharif, Arazu, Brook, Emily, Majimbi, Maimuna, Chan, Dick C., Lam, Virginie, Watts, Gerald F., Mamo, John C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978204/
https://www.ncbi.nlm.nih.gov/pubmed/36875491
http://dx.doi.org/10.3389/fendo.2023.1127481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978204/
https://www.ncbi.nlm.nih.gov/pubmed/36875491
http://dx.doi.org/10.3389/fendo.2023.1127481

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