Cargando…

Is type 2 diabetes associated dementia a microvascular early-Alzheimer’s phenotype induced by aberrations in the peripheral metabolism of lipoprotein-amyloid?

There is increasing evidence of a positive association of type 2 diabetes with Alzheimer’s disease (AD), the most prevalent form of dementia. Suggested pathways include cerebral vascular dysfunction; central insulin resistance, or exaggerated brain abundance of potentially cytotoxic amyloid-β (Aβ),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takechi, Ryusuke, Sharif, Arazu, Brook, Emily, Majimbi, Maimuna, Chan, Dick C., Lam, Virginie, Watts, Gerald F., Mamo, John C. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978204/ https://www.ncbi.nlm.nih.gov/pubmed/36875491 http://dx.doi.org/10.3389/fendo.2023.1127481

Ejemplares similares

Automated Quantitative Analysis of ex vivo Blood-Brain Barrier Permeability Using Intellesis Machine-Learning
por: Nesbit, Michael, et al.
Publicado: (2021)

In vivo retinal imaging is associated with cognitive decline, blood-brain barrier disruption and neuroinflammation in type 2 diabetic mice
por: Majimbi, May, et al.
Publicado: (2023)

Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid
por: Majimbi, Maimuna, et al.
Publicado: (2021)

Aged garlic extract as a potential prophylactic to reduce the progression of endometriosis and associated pain burden
por: Redwood, Emily, et al.
Publicado: (2022)

A Diet Enriched in Docosahexanoic Acid Exacerbates Brain Parenchymal Extravasation of Apo B Lipoproteins Induced by Chronic Ingestion of Saturated Fats
por: Pallebage-Gamarallage, Menuka M., et al.
Publicado: (2012)

The differential effects of fatty acids on enterocytic abundance of amyloid-beta
por: Galloway, Susan, et al.
Publicado: (2019)

Peripheral metabolism of lipoprotein-amyloid beta as a risk factor for Alzheimer’s disease: potential interactive effects of APOE genotype with dietary fats
por: D’Alonzo, Zachary J., et al.
Publicado: (2023)

Antioxidants and Dementia Risk: Consideration through a Cerebrovascular Perspective
por: Lam, Virginie, et al.
Publicado: (2016)

Differential Effects of High-Protein Diets Derived from Soy and Casein on Blood–Brain Barrier Integrity in Wild-type Mice
por: Snelson, Matthew, et al.
Publicado: (2017)

Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood–brain barrier function in wild-type mice
por: Takechi, Ryusuke, et al.
Publicado: (2013)

The Vitamin D, Ionised Calcium and Parathyroid Hormone Axis of Cerebral Capillary Function: Therapeutic Considerations for Vascular-Based Neurodegenerative Disorders
por: Lam, Virginie, et al.
Publicado: (2015)

Chronic Intake of Energy Drinks and Their Sugar Free Substitution Similarly Promotes Metabolic Syndrome
por: Graneri, Liam T., et al.
Publicado: (2021)

The Effects of Chronic Consumption of Lipid-Rich and Delipidated Bovine Dairy Milk on Brown Adipose Tissue Volume in Wild-Type Mice
por: D’Alonzo, Zachary J., et al.
Publicado: (2021)

Amyloid-β colocalizes with apolipoprotein B in absorptive cells of the small intestine
por: Galloway, Susan, et al.
Publicado: (2009)

Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction
por: Takechi, Ryusuke, et al.
Publicado: (2014)

Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents
por: Pallebage-Gamarallage, Menuka, et al.
Publicado: (2012)

Chronic Consumption of a Commercial Energy Drink Reduces Blood Pressure in Normotensive Wild-Type Mice
por: Graneri, Liam, et al.
Publicado: (2019)

The Consumption of Energy Drinks Induces Blood-Brain Barrier Dysfunction in Wild-Type Mice
por: Graneri, Liam, et al.
Publicado: (2021)

Aberrant Functional Connectivity of the Posterior Cingulate Cortex in Type 2 Diabetes Without Cognitive Impairment and Microvascular Complications
por: Cheng, Panpan, et al.
Publicado: (2021)

Blood-Brain Barrier Dysfunction Precedes Cognitive Decline and Neurodegeneration in Diabetic Insulin Resistant Mouse Model: An Implication for Causal Link
por: Takechi, Ryusuke, et al.
Publicado: (2017)

Circulatory disturbance of the cochlear spiral modiolar artery in a type 2 diabetic mouse model
por: Seo, Young Joon, et al.
Publicado: (2022)

The Serum Concentration of the Calcium Binding Protein S100B is Positively Associated with Cognitive Performance in Older Adults
por: Lam, Virginie, et al.
Publicado: (2013)

Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment
por: Elahy, Mina, et al.
Publicado: (2015)

Synergistic effects of high fat feeding and apolipoprotein E deletion on enterocytic amyloid-beta abundance
por: Galloway, Susan, et al.
Publicado: (2008)

Inflammation in the pathogenesis of microvascular complications in diabetes
por: Nguyen, Dung V., et al.
Publicado: (2012)

RNA interference therapy for targeting ANGPTL3 and atherogenic lipoproteins: Findings and implications of a recent phase I study
por: Watts, Gerald F., et al.
Publicado: (2023)

A Systematic Review of the MDMA Model to Address Social Impairment in Autism
por: Chaliha, Devahuti, et al.
Publicado: (2021)

Mesenchymal Stem Cell-Based Treatment for Microvascular and Secondary Complications of Diabetes Mellitus
por: Davey, Grace C., et al.
Publicado: (2014)

Editorial: Cell-Based Therapies for Diabetic Microvascular Complications
por: Bhatwadekar, Ashay D.
Publicado: (2015)

The Impaired Bioenergetics of Diabetic Cardiac Microvascular Endothelial Cells
por: Zhang, Haitao, et al.
Publicado: (2021)

The role of protein kinase C in diabetic microvascular complications
por: Pan, Deng, et al.
Publicado: (2022)

Synthesis of human amyloid restricted to liver results in an Alzheimer disease–like neurodegenerative phenotype
por: Lam, Virginie, et al.
Publicado: (2021)

Lipoprotein sialylation in atherosclerosis: Lessons from mice
por: Yu, Liming, et al.
Publicado: (2022)

New Insights Into the Regulation of Lipoprotein Metabolism by PCSK9: Lessons From Stable Isotope Tracer Studies in Human Subjects
por: Ying, Qidi, et al.
Publicado: (2021)

Familial Hypercholesterolemia and Elevated Lipoprotein(a): Cascade Testing and Other Implications for Contextual Models of Care
por: Loh, Wann Jia, et al.
Publicado: (2022)

Chronic Consumption of Bovine Dairy Milk Attenuates Dietary Saturated Fatty Acid-Induced Blood-Brain Barrier Dysfunction
por: D'Alonzo, Zachary, et al.
Publicado: (2020)

Cascade testing for elevated lipoprotein(a) in relatives of probands with high lipoprotein(a)
por: Chakraborty, Anindita, et al.
Publicado: (2022)

The impact of oxidative stress-induced mitochondrial dysfunction on diabetic microvascular complications
por: Zhang, Ziwei, et al.
Publicado: (2023)

Role of ADMA in the pathogenesis of microvascular complications in type 2 diabetes mellitus
por: Guo, Xinyang, et al.
Publicado: (2023)

Longitudinal Performance of Senescence Accelerated Mouse Prone-Strain 8 (SAMP8) Mice in an Olfactory-Visual Water Maze Challenge
por: Lam, Virginie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gdc8een93oqbt9mdilbccmp9e2