Biasing AlphaFold2 to predict GPCRs and kinases with user-defined functional or structural properties

Determining the three-dimensional structure of proteins in their native functional states has been a longstanding challenge in structural biology. While integrative structural biology has been the most effective way to get a high-accuracy structure of different conformations and mechanistic insights...

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Detalles Bibliográficos
Autores principales: Sala, Davide, Hildebrand, Peter W., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978208/
https://www.ncbi.nlm.nih.gov/pubmed/36876042
http://dx.doi.org/10.3389/fmolb.2023.1121962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978208/
https://www.ncbi.nlm.nih.gov/pubmed/36876042
http://dx.doi.org/10.3389/fmolb.2023.1121962

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