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Integration of single-cell RNA sequencing and spatial transcriptomics to reveal the glioblastoma heterogeneity
Glioblastoma (GBM), a deadly brain tumor, is still one of a few lasting challenges of contemporary oncology. Current therapies fail to significantly improve patient survival due to GBM tremendous genetic, transcriptomic, immunological, and sex-dependent heterogeneity. Over the years, clinical differ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978243/ https://www.ncbi.nlm.nih.gov/pubmed/36875988 http://dx.doi.org/10.12688/f1000research.126243.2 |