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Beclin-1 dependent autophagy improves renal outcomes following Unilateral Ureteral Obstruction (UUO) injury

BACKGROUND: Interstitial Fibrosis and Tubular Atrophy (IFTA) is the most common cause of long-term graft failure following renal transplant. One of the hallmarks of IFTA is the development of interstitial fibrosis and loss of normal renal architecture. In this study, we evaluated the role of autopha...

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Detalles Bibliográficos
Autores principales: Lopez-Soler, Reynold I., Nikouee, Azadeh, Kim, Matthew, Khan, Saman, Sivaraman, Lakshmi, Ding, Xiangzhong, Zang, Qun Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978333/
https://www.ncbi.nlm.nih.gov/pubmed/36875088
http://dx.doi.org/10.3389/fimmu.2023.1104652