Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors

Recurrent neoepitopes are cancer-specific antigens common among groups of patients and therefore ideal targets for adoptive T cell therapy. The neoepitope FSGEYIPTV carries the Rac1P29S amino acid change caused by a c.85C>T missense mutation, which is the third most common hotspot mutation in mel...

Descripción completa

Detalles Bibliográficos
Autores principales: Immisch, Lena, Papafotiou, George, Gallarín Delgado, Nerea, Scheuplein, Vivian, Paschen, Annette, Blankenstein, Thomas, Willimsky, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978334/
https://www.ncbi.nlm.nih.gov/pubmed/36875127
http://dx.doi.org/10.3389/fimmu.2023.1119498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978334/
https://www.ncbi.nlm.nih.gov/pubmed/36875127
http://dx.doi.org/10.3389/fimmu.2023.1119498

Ejemplares similares