Cargando…
Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors
Recurrent neoepitopes are cancer-specific antigens common among groups of patients and therefore ideal targets for adoptive T cell therapy. The neoepitope FSGEYIPTV carries the Rac1P29S amino acid change caused by a c.85C>T missense mutation, which is the third most common hotspot mutation in mel...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978334/ https://www.ncbi.nlm.nih.gov/pubmed/36875127 http://dx.doi.org/10.3389/fimmu.2023.1119498 |