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Elevated expression of exogenous RAD51 enhances the CRISPR/Cas9-mediated genome editing efficiency

Genome editing using CRISPR-associated technology is widely used to modify the genomes rapidly and efficiently on specific DNA double-strand breaks (DSBs) induced by Cas9 endonuclease. However, despite swift advance in Cas9 engineering, structural basis of Cas9-recognition and cleavage complex remai...

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Detalles Bibliográficos
Autores principales: Park, Seo Jung, Yoon, Seobin, Choi, Eui-Hwan, Hyeon, Hana, Lee, Kangseok, Kim, Keun Pil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978361/
https://www.ncbi.nlm.nih.gov/pubmed/36513383
http://dx.doi.org/10.5483/BMBRep.2022-0149