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Elevated expression of exogenous RAD51 enhances the CRISPR/Cas9-mediated genome editing efficiency
Genome editing using CRISPR-associated technology is widely used to modify the genomes rapidly and efficiently on specific DNA double-strand breaks (DSBs) induced by Cas9 endonuclease. However, despite swift advance in Cas9 engineering, structural basis of Cas9-recognition and cleavage complex remai...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978361/ https://www.ncbi.nlm.nih.gov/pubmed/36513383 http://dx.doi.org/10.5483/BMBRep.2022-0149 |