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The multiple combination of Paclitaxel, Ramucirumab and Elacridar reverses the paclitaxel-mediated resistance in gastric cancer cell lines

INTRODUCTION: Paclitaxel (PTX) interferes with microtubule architecture by binding to β-tubulin, thereby blocking progression at the G2/M phase and inducing apoptosis. This study aimed to investigate molecular processes underlying PTX-mediated resistance in gastric cancer (GC) cells. METHODS: PTX-me...

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Detalles Bibliográficos
Autores principales: Schirizzi, Annalisa, Contino, Marialessandra, Carrieri, Livianna, Riganti, Chiara, De Leonardis, Giampiero, Scavo, Maria Principia, Perrone, Maria Grazia, Miciaccia, Morena, Kopecka, Joanna, Refolo, Maria Grazia, Lotesoriere, Claudio, Depalo, Nicoletta, Rizzi, Federica, Giannelli, Gianluigi, Messa, Caterina, D’Alessandro, Rosalba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978398/
https://www.ncbi.nlm.nih.gov/pubmed/36874116
http://dx.doi.org/10.3389/fonc.2023.1129832