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Immunological priming of mesenchymal stromal/stem cells and their extracellular vesicles augments their therapeutic benefits in experimental graft-versus-host disease via engagement of PD-1 ligands

Mesenchymal stromal cells (MSCs) and their extracellular vesicles (EVs) exert profound anti-inflammatory and regenerative effects in inflammation and tissue damage, which makes them an attractive tool for cellular therapies. In this study we have assessed the inducible immunoregulatory properties of...

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Detalles Bibliográficos
Autores principales: Hackel, Alexander, Vollmer, Sebastian, Bruderek, Kirsten, Lang, Stephan, Brandau, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978482/
https://www.ncbi.nlm.nih.gov/pubmed/36875112
http://dx.doi.org/10.3389/fimmu.2023.1078551