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A trimeric coiled-coil motif binds bacterial lipopolysaccharides with picomolar affinity

α-helical coiled-coils are ubiquitous protein structures in all living organisms. For decades, modified coiled-coils sequences have been used in biotechnology, vaccine development, and biochemical research to induce protein oligomerization, and form self-assembled protein scaffolds. A prominent mode...

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Detalles Bibliográficos
Autores principales: Hatlem, Daniel, Christensen, Mikkel, Broeker, Nina K., Kristiansen, Per E., Lund, Reidar, Barbirz, Stefanie, Linke, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978483/
https://www.ncbi.nlm.nih.gov/pubmed/36875521
http://dx.doi.org/10.3389/fcimb.2023.1125482