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Precision enhanced alignment bonding technique with sacrificial strategy

This work proposes an “N2-1” sacrificial strategy to help to improve the accuracy of the bonding technique from the existing level. The target micropattern is copied N2 times, and (N2-1) of them are sacrificed to obtain the most accurate alignment. Meanwhile, a method for manufacturing auxiliary sol...

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Detalles Bibliográficos
Autores principales: Li, Qian, Ye, Zi, Liu, Mingyang, Liu, Wei, Zhang, Pan, Sun, Xiao, Zhang, Huimin, Li, Zhenming, Gui, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978516/
https://www.ncbi.nlm.nih.gov/pubmed/36873376
http://dx.doi.org/10.3389/fbioe.2023.1105154
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author Li, Qian
Ye, Zi
Liu, Mingyang
Liu, Wei
Zhang, Pan
Sun, Xiao
Zhang, Huimin
Li, Zhenming
Gui, Lin
author_facet Li, Qian
Ye, Zi
Liu, Mingyang
Liu, Wei
Zhang, Pan
Sun, Xiao
Zhang, Huimin
Li, Zhenming
Gui, Lin
author_sort Li, Qian
collection PubMed
description This work proposes an “N2-1” sacrificial strategy to help to improve the accuracy of the bonding technique from the existing level. The target micropattern is copied N2 times, and (N2-1) of them are sacrificed to obtain the most accurate alignment. Meanwhile, a method for manufacturing auxiliary solid alignment lines on transparent materials is proposed to visualize auxiliary marks and facilitate the alignment. Though the principle and procedure of alignment are straightforward, the alignment accuracy substantially improved compared to the original method. With this technique, we have successfully fabricated a high-precision 3D electroosmotic micropump just using a conventional desktop aligner. Because of the high precision during the alignment, the flow velocity is up to 435.62 μm/s at a driven voltage of 40 V, which far exceeds the previous similar reports. Thus, we believe that it has great potential for high precision microfluidic device fabrications.
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spelling pubmed-99785162023-03-03 Precision enhanced alignment bonding technique with sacrificial strategy Li, Qian Ye, Zi Liu, Mingyang Liu, Wei Zhang, Pan Sun, Xiao Zhang, Huimin Li, Zhenming Gui, Lin Front Bioeng Biotechnol Bioengineering and Biotechnology This work proposes an “N2-1” sacrificial strategy to help to improve the accuracy of the bonding technique from the existing level. The target micropattern is copied N2 times, and (N2-1) of them are sacrificed to obtain the most accurate alignment. Meanwhile, a method for manufacturing auxiliary solid alignment lines on transparent materials is proposed to visualize auxiliary marks and facilitate the alignment. Though the principle and procedure of alignment are straightforward, the alignment accuracy substantially improved compared to the original method. With this technique, we have successfully fabricated a high-precision 3D electroosmotic micropump just using a conventional desktop aligner. Because of the high precision during the alignment, the flow velocity is up to 435.62 μm/s at a driven voltage of 40 V, which far exceeds the previous similar reports. Thus, we believe that it has great potential for high precision microfluidic device fabrications. Frontiers Media S.A. 2023-02-16 /pmc/articles/PMC9978516/ /pubmed/36873376 http://dx.doi.org/10.3389/fbioe.2023.1105154 Text en Copyright © 2023 Li, Ye, Liu, Liu, Zhang, Sun, Zhang, Li and Gui. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Li, Qian
Ye, Zi
Liu, Mingyang
Liu, Wei
Zhang, Pan
Sun, Xiao
Zhang, Huimin
Li, Zhenming
Gui, Lin
Precision enhanced alignment bonding technique with sacrificial strategy
title Precision enhanced alignment bonding technique with sacrificial strategy
title_full Precision enhanced alignment bonding technique with sacrificial strategy
title_fullStr Precision enhanced alignment bonding technique with sacrificial strategy
title_full_unstemmed Precision enhanced alignment bonding technique with sacrificial strategy
title_short Precision enhanced alignment bonding technique with sacrificial strategy
title_sort precision enhanced alignment bonding technique with sacrificial strategy
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978516/
https://www.ncbi.nlm.nih.gov/pubmed/36873376
http://dx.doi.org/10.3389/fbioe.2023.1105154
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