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Precision enhanced alignment bonding technique with sacrificial strategy
This work proposes an “N2-1” sacrificial strategy to help to improve the accuracy of the bonding technique from the existing level. The target micropattern is copied N2 times, and (N2-1) of them are sacrificed to obtain the most accurate alignment. Meanwhile, a method for manufacturing auxiliary sol...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978516/ https://www.ncbi.nlm.nih.gov/pubmed/36873376 http://dx.doi.org/10.3389/fbioe.2023.1105154 |
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author | Li, Qian Ye, Zi Liu, Mingyang Liu, Wei Zhang, Pan Sun, Xiao Zhang, Huimin Li, Zhenming Gui, Lin |
author_facet | Li, Qian Ye, Zi Liu, Mingyang Liu, Wei Zhang, Pan Sun, Xiao Zhang, Huimin Li, Zhenming Gui, Lin |
author_sort | Li, Qian |
collection | PubMed |
description | This work proposes an “N2-1” sacrificial strategy to help to improve the accuracy of the bonding technique from the existing level. The target micropattern is copied N2 times, and (N2-1) of them are sacrificed to obtain the most accurate alignment. Meanwhile, a method for manufacturing auxiliary solid alignment lines on transparent materials is proposed to visualize auxiliary marks and facilitate the alignment. Though the principle and procedure of alignment are straightforward, the alignment accuracy substantially improved compared to the original method. With this technique, we have successfully fabricated a high-precision 3D electroosmotic micropump just using a conventional desktop aligner. Because of the high precision during the alignment, the flow velocity is up to 435.62 μm/s at a driven voltage of 40 V, which far exceeds the previous similar reports. Thus, we believe that it has great potential for high precision microfluidic device fabrications. |
format | Online Article Text |
id | pubmed-9978516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99785162023-03-03 Precision enhanced alignment bonding technique with sacrificial strategy Li, Qian Ye, Zi Liu, Mingyang Liu, Wei Zhang, Pan Sun, Xiao Zhang, Huimin Li, Zhenming Gui, Lin Front Bioeng Biotechnol Bioengineering and Biotechnology This work proposes an “N2-1” sacrificial strategy to help to improve the accuracy of the bonding technique from the existing level. The target micropattern is copied N2 times, and (N2-1) of them are sacrificed to obtain the most accurate alignment. Meanwhile, a method for manufacturing auxiliary solid alignment lines on transparent materials is proposed to visualize auxiliary marks and facilitate the alignment. Though the principle and procedure of alignment are straightforward, the alignment accuracy substantially improved compared to the original method. With this technique, we have successfully fabricated a high-precision 3D electroosmotic micropump just using a conventional desktop aligner. Because of the high precision during the alignment, the flow velocity is up to 435.62 μm/s at a driven voltage of 40 V, which far exceeds the previous similar reports. Thus, we believe that it has great potential for high precision microfluidic device fabrications. Frontiers Media S.A. 2023-02-16 /pmc/articles/PMC9978516/ /pubmed/36873376 http://dx.doi.org/10.3389/fbioe.2023.1105154 Text en Copyright © 2023 Li, Ye, Liu, Liu, Zhang, Sun, Zhang, Li and Gui. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Li, Qian Ye, Zi Liu, Mingyang Liu, Wei Zhang, Pan Sun, Xiao Zhang, Huimin Li, Zhenming Gui, Lin Precision enhanced alignment bonding technique with sacrificial strategy |
title | Precision enhanced alignment bonding technique with sacrificial strategy |
title_full | Precision enhanced alignment bonding technique with sacrificial strategy |
title_fullStr | Precision enhanced alignment bonding technique with sacrificial strategy |
title_full_unstemmed | Precision enhanced alignment bonding technique with sacrificial strategy |
title_short | Precision enhanced alignment bonding technique with sacrificial strategy |
title_sort | precision enhanced alignment bonding technique with sacrificial strategy |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978516/ https://www.ncbi.nlm.nih.gov/pubmed/36873376 http://dx.doi.org/10.3389/fbioe.2023.1105154 |
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