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Hepatitis B virus X protein induces ALDH2 ubiquitin-dependent degradation to enhance alcoholic steatohepatitis

BACKGROUND: Excessive alcohol intake with hepatitis B virus (HBV) infection accelerates chronic liver disease progression and patients with HBV infection are more susceptible to alcohol-induced liver disease. Hepatitis B virus X protein (HBx) plays a crucial role in disease pathogenesis, while its s...

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Detalles Bibliográficos
Autores principales: Zhou, Haoxiong, Wan, Sizhe, Luo, Yujun, Liu, Huiling, Jiang, Jie, Guo, Yunwei, Xiao, Jia, Wu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978578/
https://www.ncbi.nlm.nih.gov/pubmed/36875742
http://dx.doi.org/10.1093/gastro/goad006