In vivo pharmacokinetic/pharmacodynamic evaluation of cefepime/taniborbactam combination against cefepime-non-susceptible Enterobacterales and Pseudomonas aeruginosa in a murine pneumonia model

BACKGROUND: Cefepime/taniborbactam is a cephalosporin/bicyclic boronate β-lactamase inhibitor combination in clinical development for nosocomial pneumonia due to MDR Gram-negative bacteria. A murine pneumonia model was used to characterize cefepime/taniborbactam in vivo pharmacodynamics against Ente...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdelraouf, Kamilia, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978589/
https://www.ncbi.nlm.nih.gov/pubmed/36640133
http://dx.doi.org/10.1093/jac/dkac446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978589/
https://www.ncbi.nlm.nih.gov/pubmed/36640133
http://dx.doi.org/10.1093/jac/dkac446

Ejemplares similares