Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

In several neurodegenerative disorders, the neuronal proteins tau and α-synuclein adopt aggregation-prone conformations capable of replicating within and between cells. To better understand how these conformational changes drive neuropathology, we compared the interactomes of tau and α-synuclein in...

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Detalles Bibliográficos
Autores principales: Griffin, Tagan A., Schnier, Paul D., Cleveland, Elisa M., Newberry, Robert W., Becker, Julia, Carlson, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978635/
https://www.ncbi.nlm.nih.gov/pubmed/36634849
http://dx.doi.org/10.1016/j.jbc.2023.102888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978635/
https://www.ncbi.nlm.nih.gov/pubmed/36634849
http://dx.doi.org/10.1016/j.jbc.2023.102888

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