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Vibration of effect in more than 16 000 pooled analyses of individual participant data from 12 randomised controlled trials comparing canagliflozin and placebo for type 2 diabetes mellitus: multiverse analysis

OBJECTIVE: To evaluate the impact of conducting all possible pooled analyses across different combinations of randomised controlled trials and endpoints. DESIGN: Multiverse analysis, consisting of numerous pooled analyses of individual participant data. SETTING: Individual patient data from 12 rando...

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Detalles Bibliográficos
Autores principales: Gouraud, Henri, Wallach, Joshua D, Boussageon, Rémy, Ross, Joseph S, Naudet, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978683/
https://www.ncbi.nlm.nih.gov/pubmed/36936564
http://dx.doi.org/10.1136/bmjmed-2022-000154