Age-differential sexual dimorphisms in CHD8-S62X-mutant mouse synapses and transcriptomes

Chd8(+/N2373K) mice with a human C-terminal-truncating mutation (N2373K) display autistic-like behaviors in juvenile and adult males but not in females. In contrast, Chd8(+/S62X) mice with a human N-terminal-truncating mutation (S62X) display behavioral deficits in juvenile males (not females) and a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Soo Yeon, Kweon, Hanseul, Kang, Hyojin, Kim, Eunjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978779/
https://www.ncbi.nlm.nih.gov/pubmed/36873104
http://dx.doi.org/10.3389/fnmol.2023.1111388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978779/
https://www.ncbi.nlm.nih.gov/pubmed/36873104
http://dx.doi.org/10.3389/fnmol.2023.1111388

Ejemplares similares