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Current advancement in the application of prime editing

Prime editing (PE) is a precise genome manipulation technology based on the “search and replace” approach of the CRISPR-Cas9 system, while it does not require the exogenous donor DNA and the DNA double-strand breaks (DSBs). Comparing the base editing technology, the editing scope of prime editing ha...

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Detalles Bibliográficos
Autores principales: Huang, Zhangrao, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978821/
https://www.ncbi.nlm.nih.gov/pubmed/36873365
http://dx.doi.org/10.3389/fbioe.2023.1039315