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Embryonic Stem Cells Lacking DNA Methyltransferases Differentiate into Neural Stem Cells that Are Defective in Self-Renewal

BACKGROUND AND OBJECTIVES: DNA methyltransferases (Dnmts) play an important role in regulating DNA methylation during early developmental processes and cellular differentiation. In this study, we aimed to investigate the role of Dnmts in neural differentiation of embryonic stem cells (ESCs) and in m...

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Detalles Bibliográficos
Autores principales: Seo, Bong Jong, Hong, Tae Kyung, Yoon, Sang Hoon, Song, Jae Hoon, Uhm, Sang Jun, Song, Hyuk, Hong, Kwonho, Schöler, Hans Robert, Do, Jeong Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978838/
https://www.ncbi.nlm.nih.gov/pubmed/36310027
http://dx.doi.org/10.15283/ijsc22138