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Elevated Methionine Flux Drives Pyroptosis Evasion in Persister Cancer Cells

Induction of cell death represents a primary goal of most anticancer treatments. Despite the efficacy of such approaches, a small population of “persisters” develop evasion strategies to therapy-induced cell death. While previous studies have identified mechanisms of resistance to apoptosis, the mec...

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Detalles Bibliográficos
Autores principales: El-Kenawi, Asmaa, Berglund, Anders, Estrella, Veronica, Zhang, Yonghong, Liu, Min, Putney, Ryan M., Yoder, Sean J., Johnson, Joseph, Brown, Joel, Gatenby, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978888/
https://www.ncbi.nlm.nih.gov/pubmed/36480167
http://dx.doi.org/10.1158/0008-5472.CAN-22-1002