An optimized live bacterial delivery vehicle safely and efficaciously delivers bacterially transcribed therapeutic nucleic acids

There is an unmet need for delivery platforms that realize the full potential of next‐generation nucleic acid therapeutics. The in vivo usefulness of current delivery systems is limited by numerous weaknesses, including poor targeting specificity, inefficient access to target cell cytoplasm, immune...

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Detalles Bibliográficos
Autores principales: Mora, Darcy S. O., Cox, Madeline, Magunda, Forgivemore, Williams, Ashley B., Linke, Lyndsey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978928/
https://www.ncbi.nlm.nih.gov/pubmed/36874611
http://dx.doi.org/10.1002/elsc.202200037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978928/
https://www.ncbi.nlm.nih.gov/pubmed/36874611
http://dx.doi.org/10.1002/elsc.202200037

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