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Synergistic activation of AMPK by AdipoR1/2 agonist and inhibitor of EDPs–EBP interaction recover NAFLD through enhancing mitochondrial function in mice

Nonalcoholic fatty liver disease (NAFLD), especially nonalcoholic steatohepatitis (NASH), is a common hepatic manifestation of metabolic syndrome. However, there are no effective therapy to treat this devastating disease. Accumulating evidence suggests that the generation of elastin-derived peptides...

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Detalles Bibliográficos
Autores principales: Song, Nazi, Xu, Hongjiao, Wu, Shuohan, Luo, Suijia, Xu, Jingyao, Zhao, Qian, Wang, Rui, Jiang, Xianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978995/
https://www.ncbi.nlm.nih.gov/pubmed/36873175
http://dx.doi.org/10.1016/j.apsb.2022.10.003