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A SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is closely associated with coronavirus disease 2019 (COVID-19) severity and lethality. However, drugs that are effective against inflammation to treat lethal COVID-19 are still urgently needed. Here, we constructed a...

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Detalles Bibliográficos
Autores principales: Xia, Lin, Yuan, Lun-zhi, Hu, Ya-hong, Liu, Jun-yi, Hu, Guo-sheng, Qi, Ruo-yao, Zhang, Tian-ying, Xiong, Hua-long, Zheng, Zao-zao, Lin, Hong-wei, Zhang, Jia-mo, Yu, Chao, Zhou, Ming, Ma, Jian, Cheng, Tong, Chen, Ri-rong, Guan, Yi, Xia, Ning-shao, Liu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979130/
https://www.ncbi.nlm.nih.gov/pubmed/36864189
http://dx.doi.org/10.1038/s41423-023-00985-3