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Reappraisal of oxidized HMGB1 as a mediator and biomarker

HMGB1 is a dual-function protein that acts as a chromatin-binding protein and as a danger-associated molecular pattern (DAMP) when released from activated immune cells or injured tissue. In much of the HMGB1 literature, immunomodulatory effects of extracellular HMGB1 are proposed to depend on its ox...

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Detalles Bibliográficos
Autores principales: Pirnie, Ross, P Gillespie, Kevin, Mesaros, Clementina, Blair, Ian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979160/
https://www.ncbi.nlm.nih.gov/pubmed/36874369
http://dx.doi.org/10.2144/fsoa-2022-0052