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Reappraisal of oxidized HMGB1 as a mediator and biomarker
HMGB1 is a dual-function protein that acts as a chromatin-binding protein and as a danger-associated molecular pattern (DAMP) when released from activated immune cells or injured tissue. In much of the HMGB1 literature, immunomodulatory effects of extracellular HMGB1 are proposed to depend on its ox...
Autores principales: | Pirnie, Ross, P Gillespie, Kevin, Mesaros, Clementina, Blair, Ian A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979160/ https://www.ncbi.nlm.nih.gov/pubmed/36874369 http://dx.doi.org/10.2144/fsoa-2022-0052 |
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