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Iron-based and BRD(4)-downregulated strategy for amplified ferroptosis based on pH-sensitive/NIR-II-boosted nano-matchbox

Ferroptosis (FPT), a novel form of programmed cell death, is characterized by overwhelming iron/reactive oxygen species (ROS)-dependent accumulation of lipid peroxidation (LPO). However, the insufficiency of endogenous iron and ROS level limited the FPT therapeutic efficacy to a large extent. To ove...

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Detalles Bibliográficos
Autores principales: Geng, Lujing, Lu, Tong, Jing, Huaqing, Zhou, Yue, Liang, Xiaoyang, Li, Jiao, Li, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979193/
https://www.ncbi.nlm.nih.gov/pubmed/36873167
http://dx.doi.org/10.1016/j.apsb.2022.05.011