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Iron-based and BRD(4)-downregulated strategy for amplified ferroptosis based on pH-sensitive/NIR-II-boosted nano-matchbox
Ferroptosis (FPT), a novel form of programmed cell death, is characterized by overwhelming iron/reactive oxygen species (ROS)-dependent accumulation of lipid peroxidation (LPO). However, the insufficiency of endogenous iron and ROS level limited the FPT therapeutic efficacy to a large extent. To ove...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979193/ https://www.ncbi.nlm.nih.gov/pubmed/36873167 http://dx.doi.org/10.1016/j.apsb.2022.05.011 |