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Pseudouridimycin—A Potent Nucleoside Inhibitor of the RNA Polymerase Beta Prime Subunit of Streptococcus pyogenes

[Image: see text] Streptococcus pyogenes (group A streptococcus, GAS), a Gram-positive bacterium, is a major cause of mild to severe life-threatening infections. Antibacterial resistance to penicillin and macrolides poses a major threat in the treatment of GAS and necessitates alternate drugs and ne...

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Detalles Bibliográficos
Autores principales: Pavundurai Chandra, Kunthavai, Perumal, Damodharan, Ragunathan, Preethi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979225/
https://www.ncbi.nlm.nih.gov/pubmed/36873015
http://dx.doi.org/10.1021/acsomega.2c07805